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KMID : 0359920100290060772
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Korean Journal of Nephrology
2010 Volume.29 No. 6 p.772 ~ p.775
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Proliferative Glomerulopathy with Unusual Subendothelial Deposits of Striated Structure in Multiple Myeloma
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Lee Yun-Gyoo
Shin Dong-Yeop
Lee Hyun-Jung
Choi Se-Youn
Park Jae-Yoon
Ahn Shin-Young
Lee Ha-Jeong
Oh Yun-Jung
Moon Kyung-Chul
Oh Kook-Hwan
Kim In-Ho
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Abstract
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A 50-year-old woman was admitted for the evaluation of proteinuria and renal biopsy. On the basis of the serum monoclonal protein, marrow plasma cell dyscrasia and end organ damage (nephritic range proteinuria), multiple myeloma was diagnosed. A renal biopsy showed a membranoproliferative glomerulonephritis pattern of injury and unusual organized deposits of striated structure in the subendothelial space, which were identified as non-amyloid non-immunoglobulin-derived deposits. These deposits contained regularly stacked straight electron-dense bands, which have not been described in the setting of paraproteinemia and/or plasma cell dyscrasia.
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KEYWORD
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Membranoproliferative glomerulonephritis, Deposit, Striated, Monoclonal gammopathy
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